クマリン

Coumarin is a fragrant organic compound with the chemical formula C9H6O2, naturally found in plants like tonka beans, cinnamon, and sweet clover. It has a distinctive sweet, vanilla-like aroma, making it valuable in perfumery and flavoring. Synthetically produced coumarin is widely used due to cost efficiency and purity control. While approved for cosmetic and industrial uses, its ingestion is restricted in food products in many countries due to potential liver toxicity at high doses. Its versatile structure also serves as a backbone for pharmaceutical derivatives like anticoagulants.

Coumarin Application

Coumarin is primarily used in fragrances and cosmetics for its warm, woody scent, enhancing soaps, detergents, and perfumes. In manufacturing, it acts as a precursor for anticoagulant drugs like warfarin. The compound also functions as a fluorescent dye in lasers and OLEDs due to its light-emitting properties. Historically, it flavored foods, but most nations now ban this use. Additionally, it serves in electroplating baths and as an optical brightener in textiles. Research continues into its potential medical applications, including anti-inflammatory and anticancer effects.

Coumarin Features

Key features include a melting point of 68-70°C, volatility for easy incorporation into scents, and stable fluorescence under UV light. Its benzopyrone structure allows chemical modifications for diverse industrial uses. While non-toxic in topical applications, oral consumption risks hepatotoxicity, prompting regulatory limits. Natural coumarins exhibit plant defense properties, while synthetic versions offer consistency for commercial use. The compound’s dual role as a fragrance and functional molecule maintains its relevance in niche scientific and industrial sectors despite safety constraints.