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トリス(ヒドロキシメチル)アミノメタン

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トリス; 医薬中間体; 生物学的緩衝剤。

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説明
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説明

 

化学名

トリス(ヒドロキシメチル)アミノメタン

別名

トリスベース;トリスバッファー

CAS番号

77-86-1

分子式

C4H11NO3

分子量

121.14

分子構造

 

詳細

外観

White crystalline powder

Assay  

99.9%以上

融点

168.0 – 171 ℃

溶解度(40%水溶液)

無色透明の溶液

重金属

最大5ppm

乾燥減量

最大0.2%

pH値(5%水溶液)

10.0-11.5

鉄イオン(Fe3+)

1 ppm max.

硫酸塩(SO42-)

最大10ppm。

塩化物(Cl-)

最大3ppm。

紫外線吸収度 260 nm(20%水溶液)

最大0.07。

紫外線吸収度 260 nm(40%水溶液)

最大0.07。

紫外線吸収度 280 nm(40%水溶液)

最大0.07。

紫外線吸収度 290 nm(40%水溶液)

最大0.05。

紫外線吸光度 400 nm(40%水溶液)

最大0.02。

燃焼残留物

0.05%以下。

 

主な用途

トリス(ヒドロキシメチル)アミノメタンは、界面活性剤、加硫促進剤、医薬品の合成に使用できます。化粧品クリームやローション、鉱油やパラフィンワックスの乳剤、皮革用ドレッシング、繊維製品、磨き剤、洗浄剤、いわゆる可溶性油の乳化剤として使用できます。酸性ガスの吸収剤。生物学的緩衝剤。

 

Tris(hydroxymethyl)aminomethane (commonly known as Tris) is a widely used buffering agent in various laboratory, pharmaceutical, and industrial applications. Its chemical formula is C4H11NO3, and it is a colorless, crystalline powder that is highly soluble in water. Tris is commonly used to maintain the pH stability of solutions, making it essential in biochemical and biological research.

 

Key Features & Benefits:

- Effective pH Buffer: Tris acts as an excellent buffer, maintaining the pH range of 7.0 to 9.0, ideal for many biochemical and molecular biology experiments.

- High Purity: Available in high-purity forms, ensuring reliable and consistent results in critical applications.

- Stability: Tris exhibits good thermal and chemical stability, making it suitable for use in various conditions.

- Versatility: It is widely used in applications ranging from protein analysis, enzyme activity studies, to DNA/RNA experiments.

- Biocompatibility: Non-toxic and safe for use in biological and pharmaceutical research.

 

Applications:

  1. Biochemical and Molecular Biology: Tris is a key component in buffer solutions, commonly used in electrophoresis, western blotting, PCR, and enzyme assays.
  2. Pharmaceutical Industry: Used in the formulation of injectable drugs and vaccine development to stabilize pH and enhance product performance.
  3. Industrial Applications: Used in water treatment, cosmetic formulations, and other chemical processes to maintain stable pH levels.

 

Packaging & Storage:

Tris is typically available in 25 kg bags or smaller packaging for laboratory use. It should be stored in a cool, dry place to maintain its stability and effectiveness.

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