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Azure II Biological Stain CAS 37247102 China Suppliers and Factory
Azure II is a high-performance synthetic basic dye from the thiazine class, meticulously engineered for precision biological staining and microscopic analysis. Chemically recognized as 3-Amino-7-dimethylamino-2-methylphenothiazin-5-ium chloride, this blue-green reagent is an indispensable tool in hematology and histology, specifically optimized for the visualization of chromatin and nucleic acids.
Due to its distinct cationic properties, Azure II exhibits a powerful affinity for acidic cellular components, ensuring high-contrast differentiation in blood smears and histological preparations. Its unique metachromatic capabilities allow it to display varying colors depending on the tissue element it binds to, making it a critical component in Romanowsky-type stains like Wright-Giemsa for advanced pathological examinations.
Detailed Parameters
| Chemical Name | Azure II | CAS No. | 37247-10-2 | |
|---|---|---|---|---|
| Molecular Formula | C16H18ClN3S.C15H16ClN3S | Molecular Weight | 625.68 | |
| Appearance | Bottle green powder | Biological Test | Pass Test | |
| Ignition Residue | 23.5% max (SO4) | Packaging | 25kg / Fibre Drum | |
| Main Application | Biological Dyeing Agents | Chemical Class | Thiazine Dye |
Key Advantages
High Binding Affinity
Strong cationic binding to acidic cellular components ensures stable and clear visualization of nucleic acids.
Rapid Staining Speed
Optimized molecular structure allows for efficient penetration of cellular membranes, reducing processing time.
Metachromatic Precision
Capable of displaying multiple colors to differentiate various tissue elements with extreme accuracy.
High Contrast Imaging
Produces sharp, high-contrast results essential for diagnostic pathology and hematology.
Reproducible Results
Consistent chemical purity ensures standardized results across different medical laboratory batches.
Versatile Application
Effective in flow cytometry, cytogenetics, and traditional histological section staining.
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Management Platforms
Quality Control
Strict batch testing for biological dyeing pass rates to ensure diagnostic accuracy.
Formulation Support
Expert guidance on combining Azure II with eosin for optimal Romanowsky staining.
Stability Monitoring
Continuous monitoring of powder stability and ignition residue levels.
Pure Synthesis
Advanced chemical synthesis pathways to minimize impurities in the thiazine structure.
Secure Logistics
Industrial-grade fibre drum packaging ensuring moisture-proof transport worldwide.
Regulatory Compliance
Full compliance with specialty chemical manufacturing standards for laboratory reagents.
Investment Return Comparison
| Metric | Standard Reagents | Azure II (Premium) |
|---|---|---|
| Staining Clarity | Moderate | Ultra-High Contrast |
| Diagnostic Accuracy | Basic | Professional Grade |
| Binding Stability | Variable | Strong Cationic Bind |
| Batch Consistency | Standard | Highly Reproducible |
| Tissue Versatility | Limited | Broad (Blood, Nerve, Microbes) |
Frequently Asked Questions
Azure II is primarily used as a biological staining reagent for differential white blood cell counting and the identification of malaria parasites in peripheral blood smears.
Azure II is a chemical histological dye used in microscopy. It is entirely unrelated to Microsoft's Azure cloud computing platform.
Metachromasia allows Azure II to change its apparent color when binding to different tissue elements, which is critical for identifying mast cells and cartilage components.
Yes, it is frequently combined with dyes like eosin in Romanowsky-type stains (e.g., Wright-Giemsa) to enhance cellular differentiation during pathological examinations.
Our Azure II is supplied in 25kg fibre drums, designed to maintain the purity and stability of the bottle green powder during transit.
It is used in cytogenetics for chromosome banding, staining neural tissues, and as a counterstain in flow cytometry and immunocytochemistry to highlight nuclei.
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