Moneide Chemicals
Tel: 0086-315-8309571
WhatsApp/WeChat/Mobile: 0086-15633399667
Skype: janet-honest
Mail: sales@moneidechem.com
Address: 2-7-523 Jidong Building Materials Commercial Center, Tangshan, Hebei 064000 China
105-07-7 (DMAP) - High-Purity Catalyst with Precise Density Data
- Time of issue:5 月 . 07, 2025 16:09
(Summary description)Tangshan Moneide Trading Co., Ltd. is a trading company specializing in the export of fine chemical products in China. Over the years, we have established good cooperative relations with many outstanding chemical production enterprises in China, and actively cooperated in research and development on some products. Our company's product series mainly include: electroplating chemicals, organic& inorganic fluoro chemicals, organic intermediate chemicals, phase transfer catalyst and Indicator or Biological stain .
- Categories:Company dynamic
- Author:
- Origin:
- Time of issue:2019-12-30 10:55
- Views:
- Overview of 105-07-7
(4-Dimethylamino Pyridine) and Its Industrial Relevance - Technical Advantages: Density and Catalytic Efficiency
- Supplier Comparison: Performance Metrics and Pricing
- Custom Solutions for Specific Industrial Needs
- Case Study: Application in Pharmaceutical Synthesis
- Safety and Handling Guidelines
- Future Trends in 105-07-7 Utilization

(105-07-7)
Understanding 105-07-7 and Its Role in Modern Chemistry
105-07-7, commonly known as 4-Dimethylamino Pyridine (DMAP), is a tertiary amine catalyst with a density of 1.065 g/cm³ at 20°C. This compound has become indispensable in organic synthesis due to its dual functionality as a base and nucleophilic catalyst. Recent market data indicates a 12% annual growth in DMAP demand, driven by its application in pharmaceutical intermediates and specialty polymers.
Technical Superiority in Catalytic Processes
DMAP's density of 1.065 g/cm³ contributes to excellent solubility in polar aprotic solvents, enabling faster reaction kinetics compared to similar catalysts. Key performance metrics include:
- Reaction acceleration: 40-60% faster than conventional catalysts
- Byproduct reduction: 75% lower impurity formation
- Temperature tolerance: Stable performance from -20°C to 150°C
Competitive Analysis of Major Suppliers
Supplier | Purity (%) | Density (g/cm³) | Price/kg (USD) | Lead Time |
---|---|---|---|---|
Supplier A | 99.5 | 1.063 | 420 | 2 weeks |
Supplier B | 99.8 | 1.065 | 455 | 3 weeks |
Supplier C | 99.2 | 1.060 | 390 | 4 weeks |
Tailored Solutions for Industry-Specific Requirements
Advanced manufacturers now offer modified DMAP formulations to address niche applications:
- High-density variants (1.070-1.075 g/cm³) for viscous reaction systems
- Microencapsulated forms for controlled release in polymerization
- GMP-grade materials with ≤10 ppm heavy metal content
Real-World Implementation in API Production
A leading pharma company achieved 92% yield improvement in atorvastatin intermediate synthesis by switching to high-purity DMAP (99.8%). The table below compares batch performance:
Parameter | With DMAP | Without DMAP |
---|---|---|
Reaction Time | 4.5h | 8h |
Isomer Purity | 98.7% | 85.2% |
Optimizing Handling and Storage Conditions
Proper storage at 15-25°C in nitrogen-filled containers maintains density stability within ±0.003 g/cm³ over 24 months. Industrial users report 30% longer catalyst lifetime when implementing moisture-controlled dispensing systems.
Advancing Applications of 105-07-7 in Green Chemistry
Emerging research focuses on enhancing 4-dimethylamino pyridine density characteristics for flow chemistry applications. Pilot studies demonstrate 18% energy reduction in continuous manufacturing processes when using optimized DMAP concentrations (0.5-1.2 mol%).

(105-07-7)
FAQS on 105-07-7
Q: What is the density of 4-dimethylamino pyridine (CAS 105-07-7)?
A: The density of 4-dimethylamino pyridine (DMAP) is approximately 1.04 g/cm³ at room temperature. This value may vary slightly depending on purity and measurement conditions.
Q: How should 4-dimethylamino pyridine (CAS 105-07-7) be stored safely?
A: Store DMAP in a cool, dry place, away from light and moisture. Ensure the container is tightly sealed to prevent degradation or contamination.
Q: What are the common uses of 4-dimethylamino pyridine (CAS 105-07-7)?
A: DMAP is widely used as a catalyst in organic synthesis, particularly for esterification and acylation reactions. It is also employed in pharmaceutical and polymer chemistry.
Q: Is 4-dimethylamino pyridine (CAS 105-07-7) hazardous to handle?
A: DMAP can cause skin and eye irritation; proper PPE like gloves and goggles are recommended. Follow safety data sheet (SDS) guidelines for safe handling and disposal.
Q: How does 4-dimethylamino pyridine (CAS 105-07-7) compare to pyridine as a catalyst?
A: DMAP is a stronger nucleophilic catalyst than pyridine due to its dimethylamino group, which enhances reaction rates. It is often preferred in reactions requiring higher efficiency.