TC-DEP 50 N,N-Diethyl-2-Propyn-1-Amine Sulfate

N,N-Diethyl-2-propyn-1-amine sulfate is a specialized organic compound commonly used as an intermediate in chemical synthesis. With the molecular formula C7H13NS·H2SO4, this compound is typically encountered as a crystalline or powdered sulfate salt, enhancing its stability and handling properties compared to the free amine form.

This compound features both a tertiary amine group and a terminal alkyne (propyne) functional group, giving it unique chemical reactivity. These dual functionalities make it highly valuable in the pharmaceutical industry, where it is often used as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system or with antispasmodic properties.

Its terminal alkyne structure allows it to participate in “click chemistry”, especially azide-alkyne cycloaddition reactions, which are widely used in medicinal chemistry and drug development for constructing complex molecules efficiently and selectively. The compound is also studied in the development of neuroprotective agents and enzyme inhibitors.

Beyond pharmaceuticals, N,N-Diethyl-2-propyn-1-amine sulfate finds application in agrochemical synthesis and fine chemical production, where its structure can be leveraged to introduce reactive alkyne moieties into larger molecules. It can also serve as a functional additive or modifying agent in polymer chemistry.

When handling this compound, appropriate safety precautions should be taken, including the use of gloves, eye protection, and adequate ventilation. It should be stored in a tightly sealed container in a cool, dry place, away from incompatible substances.

In summary, N,N-Diethyl-2-propyn-1-amine sulfate is a versatile intermediate with important applications in drug synthesis, materials science, and chemical research, valued for its functional versatility and synthetic potential.