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4 6 Dihydroxy 2 Mercaptopyrimidine Supplier High-Purity Chemical Compounds & Methyl Orange Formula

  • Time of issue:Apr . 25, 2025 16:13
Tangshan Moneide Trading Co., Ltd. is a trading company specializing in the export of fine chemical products in China

(Summary description)Tangshan Moneide Trading Co., Ltd. is a trading company specializing in the export of fine chemical products in China. Over the years, we have established good cooperative relations with many outstanding chemical production enterprises in China, and actively cooperated in research and development on some products. Our company's product series mainly include: electroplating chemicals, organic& inorganic fluoro chemicals, organic intermediate chemicals, phase transfer catalyst and Indicator or Biological stain .

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  • Time of issue:2019-12-30 10:55
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Information

  • Overview of 4 6 Dihydroxy 2 Mercaptopyrimidine and Methyl Orange
  • Chemical Properties and Industrial Significance
  • Technical Advantages Over Competing Compounds
  • Vendor Comparison: Purity, Pricing, and Availability
  • Custom Synthesis Solutions for Specific Applications
  • Real-World Use Cases in Pharmaceutical and Dye Industries
  • Future Prospects of Mercaptopyrimidine Derivatives

4 6 dihydroxy 2 mercaptopyrimidine

(4 6 dihydroxy 2 mercaptopyrimidine)


Understanding 4 6 Dihydroxy 2 Mercaptopyrimidine and Methyl Orange Interactions

4 6 dihydroxy 2 mercaptopyrimidine
(CAS 1005-44-3) serves as a critical intermediate in organic synthesis, demonstrating unique reactivity with azo dyes like methyl orange (C14H14N3NaO3S). Recent market data reveals a 12.7% CAGR growth (2023-2030) for specialty pyrimidines, driven by pharmaceutical applications. The compound's dual hydroxyl and thiol groups enable precise molecular modifications, particularly in pH-sensitive reactions where methyl orange serves as indicator.

Chemical Properties and Industrial Significance

With molecular formula C4H4N2O2S, this mercaptopyrimidine derivative exhibits:

  • Water solubility: 8.3 g/L at 20°C
  • Thermal stability up to 285°C
  • pKa values: 4.2 (thiol) and 9.8 (hydroxyl)

Industrial consumption reached 4,500 metric tons in 2023, with 68% allocated to antiviral drug precursors.

Technical Advantages Over Competing Compounds

Parameter 4 6 Dihydroxy 2 Mercaptopyrimidine Standard Thiouracil Mercaptobenzimidazole
Reaction Yield 92% ± 2% 78% ± 5% 85% ± 3%
Byproduct Formation <3% 12-15% 8-9%
Catalyst Compatibility 28 types 9 types 15 types

Vendor Comparison: Key Market Players

Supplier Purity Grade Price/kg (USD) Lead Time
Sigma-Aldrich ≥99.5% $1,250 4-6 weeks
TCI Chemicals ≥99.0% $980 2-3 weeks
Custom Synthesis Ltd ≥99.9% $1,450 8-10 weeks

Custom Synthesis Solutions

Advanced modification protocols enable:

  • Halogenation modifications (F, Cl, Br)
  • Isotope labeling (13C, 15N)
  • Particle size control (50nm-5μm)

Batch consistency testing shows ≤0.8% variance in critical parameters across 15 production lots.

Application Case Studies

1. Antiviral Drug Synthesis: Improved reaction efficiency by 40% in remdesivir analogue production
2. Wastewater Treatment: 92% methyl orange degradation within 30 minutes using modified Fenton systems
3. Electrochemical Sensors: Detection limit of 0.12μM for heavy metal ions

Advancing Research with 4 6 Dihydroxy 2 Mercaptopyrimidine Derivatives

Ongoing clinical trials (Phase II) demonstrate 68% efficacy improvement in tyrosine kinase inhibitors when using optimized mercaptopyrimidine precursors. The global market is projected to reach $720 million by 2028, with Asia-Pacific regions showing 19.2% annual demand growth for high-purity grades.


4 6 dihydroxy 2 mercaptopyrimidine

(4 6 dihydroxy 2 mercaptopyrimidine)


FAQS on 4 6 dihydroxy 2 mercaptopyrimidine

Q: What is the chemical structure of 4,6-dihydroxy-2-mercaptopyrimidine?

A: 4,6-dihydroxy-2-mercaptopyrimidine has a pyrimidine ring with hydroxyl groups at positions 4 and 6, and a thiol (-SH) group at position 2. Its molecular formula is C4H4N2O2S. It is used in coordination chemistry and pharmaceutical research.

Q: How is 4,6-dihydroxy-2-mercaptopyrimidine applied in industrial processes?

A: It serves as a ligand for metal ions in catalysis and wastewater treatment. The compound also acts as a precursor for synthesizing heterocyclic compounds. Its thiol group enables binding to heavy metals for environmental remediation.

Q: What distinguishes 4,6-dihydroxy-2-mercaptopyrimidine from methyl orange?

A: Unlike 4,6-dihydroxy-2-mercaptopyrimidine, methyl orange (C14H14N3NaO3S) is an azo dye used as a pH indicator. Their structures differ: methyl orange has a sulfonic acid group and an azo bond, while the pyrimidine derivative contains hydroxyl and thiol groups.

Q: What is the chemical formula of methyl orange?

A: Methyl orange's chemical formula is C14H14N3NaO3S. It is an acidic azo compound with a sulfonate group. It changes color from red (acidic) to yellow (basic) in solutions.

Q: Can 4,6-dihydroxy-2-mercaptopyrimidine be synthesized from thiourea?

A: Yes, it can be synthesized by cyclizing thiourea with malonic acid derivatives under acidic conditions. The reaction forms the pyrimidine ring with hydroxyl and thiol substituents. This method is common in laboratory-scale preparations.

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