Moneide Chemicals
Tel: 86-315-8309571
WhatsApp/WeChat/Mobile: 0086-15633399667
Skype: janet-honest
Mail: janet-honest@hotmail.com
Address: 2-7-523 Jidong Building Materials Tangshan, Hebei 064000 China
Tetrabutyl Ammonium Tribromide
Chemical Name |
Tetrabutyl ammonium tribromide |
Synonyms |
Tetra-n-butylammonium tribromide; TBABr3 |
CAS No. |
38932-80-8 |
Molecular formula |
C16H36Br3N-2 |
Molecular weight |
482.18 |
Molecular Structure |
|
Details |
Appearance: orange powder Purity: 99.0% min. |
Main Application |
It is mainly used as bromination reagent and catalyst. In organic synthesis, it can selectively brominated the phenols, aromatic amines, acetylaryl amines, methyl ketones, olefins, alkynes, alcohols and other substances.
|
- Bromination Reactions: It is widely used as a brominating agent in organic synthesis. For example, in the bromination of alkenes, Tetrabutyl Ammonium Tribromide can selectively add bromine atoms across the double bond, forming dibromo - substituted products. This reaction is highly regioselective and stereoselective in many cases, allowing for the synthesis of specific brominated compounds with well - defined structures.
- Oxidation Reactions: In addition to bromination, it can also be employed in oxidation reactions. For instance, it can oxidize certain sulfur - containing compounds, such as thiols to disulfides, or it can be used to oxidize alcohols to carbonyl compounds under specific reaction conditions. These oxidation reactions are important in the synthesis of various organic molecules, including pharmaceuticals and fine chemicals.
- Intermediate in Drug Synthesis: Tetrabutyl Ammonium Tribromide plays a crucial role as an intermediate in the synthesis of many pharmaceutical compounds. It participates in reactions that build the complex molecular structures required for drugs. In the synthesis of certain anti - cancer drugs, for example, it may be involved in introducing bromine atoms or facilitating oxidation steps, which are essential for the drug's activity and efficacy.
- Process Optimization: Its use in pharmaceutical manufacturing processes can optimize reaction conditions, reduce reaction times, and improve product purity. By using this reagent, pharmaceutical companies can enhance the efficiency of drug production while maintaining high - quality standards.
- Polymer Modification: In polymer science, Tetrabutyl Ammonium Tribromide can be used to modify polymers. It can introduce bromine atoms into polymer chains, which can change the polymer's properties such as its flame retardancy, solubility, and reactivity. This is valuable in the production of polymers for applications where specific property enhancements are required, such as in the manufacturing of flame - retardant plastics for electronics and construction materials.
- Cross - Linking Agent: It can also act as a cross - linking agent in certain polymer systems. By promoting cross - linking reactions, it can improve the mechanical properties of polymers, such as their strength and toughness. This is useful in the synthesis of high - performance polymers for applications in the automotive and aerospace industries.
- Tetrabutyl Ammonium Tribromide is harmful if swallowed, inhaled, or absorbed through the skin.
- It is a strong oxidizing agent and can cause severe burns and eye damage. Contact with combustible materials can pose a fire hazard.
- Prolonged or repeated exposure may have adverse effects on health.
- When handling this product, always wear appropriate personal protective equipment, including chemical - resistant gloves, safety goggles with side - shields, and a lab coat or protective apron.
- Work in a well - ventilated area, preferably under a fume hood, to avoid inhalation of dust or fumes.
- In case of contact with skin, immediately remove contaminated clothing and rinse the affected area with plenty of water for at least 15 minutes. Seek medical attention promptly. If the compound gets into the eyes, rinse the eyes with copious amounts of water for at least 15 minutes, lifting the eyelids occasionally, and then seek immediate medical help.
- Keep away from heat, sparks, and open flames. Store it in a cool, dry place away from flammable and combustible materials.
- Store Tetrabutyl Ammonium Tribromide in a cool, dry place, away from direct sunlight and heat sources.
- Keep it in a tightly sealed container to prevent moisture absorption and contact with air, which could potentially affect its chemical properties.
- Store it separately from incompatible substances such as reducing agents, flammable materials, and strong acids to avoid dangerous reactions.