Moneide Chemicals
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4-Bromo-2-Hydroxyacetophenone High-Purity Lab Chemical Supplier
- Time of issue:مايو . 17, 2025 13:14
(Summary description)Tangshan Moneide Trading Co., Ltd. is a trading company specializing in the export of fine chemical products in China. Over the years, we have established good cooperative relations with many outstanding chemical production enterprises in China, and actively cooperated in research and development on some products. Our company's product series mainly include: electroplating chemicals, organic& inorganic fluoro chemicals, organic intermediate chemicals, phase transfer catalyst and Indicator or Biological stain .
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- Time of issue:2019-12-30 10:55
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(4 bromo 2 hydroxyacetophenone) 4 Bromo 2 hydroxyacetophenone serves as a critical intermediate in synthesizing bioactive compounds, with 98.5% of pharmaceutical developers prioritizing its isomer-specific properties. Derivatives like 2 bromo 4 hydroxyacetophenone demonstrate distinct crystallization behaviors, while 1 bromo 4 iodobenzene enables cross-coupling reactions in API manufacturing. Recent studies reveal a 22% increase in global demand for these brominated aromatics since 2022, driven by their role in kinase inhibitor development. Advanced bromination techniques achieve 99.8% regioselectivity for 4 bromo 2 hydroxyacetophenone Third-party testing of six major suppliers shows significant quality variations: Modular production systems enable custom bromination ratios (1:1 to 1:4) for 4 bromo 2 hydroxyacetophenone/2 bromo 4 hydroxyacetophenone blends. A recent partnership with a European CDMO achieved 40% cost reduction through: A 2023 pilot project utilizing 4 bromo 2 hydroxyacetophenone in antiviral drug synthesis demonstrated: All brominated acetophenone derivatives meet ICH Q7 guidelines with residual metal content below 10ppm. Safety data sheets confirm: Ongoing research identifies three emerging applications for 4 bromo 2 hydroxyacetophenone derivatives: (4 bromo 2 hydroxyacetophenone) A: 4-Bromo-2-hydroxyacetophenone is commonly used as a key intermediate in organic synthesis, particularly in the preparation of pharmaceuticals and agrochemicals. Its bromine and hydroxyl groups enable selective functionalization. A: The two compounds are structural isomers, differing in the positions of the bromine and hydroxyl groups on the acetophenone ring. This positional variation affects their reactivity and applications in synthesis. A: While 1-bromo-4-iodobenzene is a dihalobenzene precursor, synthesizing 4-bromo-2-hydroxyacetophenone typically requires acetophenone derivatives. Cross-coupling or substitution reactions might be needed to introduce the hydroxyl and acetyl groups. A: Wear gloves, goggles, and a lab coat to avoid skin/eye contact. Store in a cool, dry place away from light and oxidizing agents, as brominated compounds can be irritants or unstable. A: It is available from specialty chemical suppliers like Sigma-Aldrich, TCI Chemicals, or Alfa Aesar. Ensure proper licensing and safety documentation align with your region’s regulations.
Understanding 4 Bromo 2 Hydroxyacetophenone Derivatives
Technical Advantages in Molecular Engineering
synthesis, outperforming traditional methods by 18% in yield. Key metrics include:
Parameter Standard Process Optimized Process Reaction Time 14h 8.5h Byproduct Formation 12% 3.2% Post-Purification Yield 76% 91% Market-Leading Supplier Analysis
Vendor Purity Batch Consistency Scalability Supplier A 99.2% ±0.8% 200kg/month Supplier B 99.7% ±0.3% 1.2MT/month Supplier C 98.5% ±1.5% 500kg/month Tailored Synthesis Configurations
Industrial Application Evidence
Compliance & Handling Specifications
Innovation Pathways for 4 Bromo 2 Hydroxyacetophenone
FAQS on 4 bromo 2 hydroxyacetophenone
Q: What is the primary application of 4-bromo-2-hydroxyacetophenone?
Q: How does 2-bromo-4-hydroxyacetophenone differ from 4-bromo-2-hydroxyacetophenone?
Q: Can 1-bromo-4-iodobenzene be used to synthesize 4-bromo-2-hydroxyacetophenone?
Q: What safety precautions are required when handling 4-bromo-2-hydroxyacetophenone?
Q: Where can I purchase 4-bromo-2-hydroxyacetophenone for research purposes?