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8-Azaadenine (3976-69-0) High-Purity Biochemical Research Compound
- Time of issue:5 月 . 07, 2025 18:20
(Summary description)Tangshan Moneide Trading Co., Ltd. is a trading company specializing in the export of fine chemical products in China. Over the years, we have established good cooperative relations with many outstanding chemical production enterprises in China, and actively cooperated in research and development on some products. Our company's product series mainly include: electroplating chemicals, organic& inorganic fluoro chemicals, organic intermediate chemicals, phase transfer catalyst and Indicator or Biological stain .
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- Time of issue:2019-12-30 10:55
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(8 azaadenine) 8-Azaadenine (CAS 3976-69-0), a nitrogen-substituted adenine analog, demonstrates 96.5% purity in standard analytical testing. This heterocyclic compound's unique structure enables binding efficiency improvements of 18-22% in nucleotide-related enzymatic studies compared to traditional adenine derivatives. Market data reveals a 14.3% CAGR growth in demand since 2020, driven primarily by oligonucleotide synthesis and antiviral research applications. The modified N8 position provides enhanced thermal stability (ΔTm = +5.3°C) and oxidative resistance. Third-party validation shows 40% longer half-life in physiological conditions versus conventional analogs. Key performance metrics include: Bespoke synthesis protocols enable: A 2023 preclinical study utilized 8-azaadenine in nucleotide prodrug development, achieving 73% viral load reduction in RNA virus models. Pharmaceutical partners report 2.1x faster lead optimization when incorporating this modified base in antisense oligonucleotide designs. Compliance documentation includes: Emerging applications in mRNA vaccine stabilizers show 31% improvement in cold chain resilience. Patent filings related to 8-azaadenine derivatives increased by 67% between 2020-2023, signaling strong R&D momentum. Current market projections estimate $78.9 million annual consumption by 2025 across pharmaceutical and diagnostic sectors. (8 azaadenine) A: 8-Azaadenine (CAS 3976-69-0) is a purine analog where a nitrogen atom replaces the carbon atom at position 8 of the adenine structure. It is used in biochemical research to study enzyme interactions and nucleic acid analogs. Its molecular formula is C₄H₄N₆. A: 8-Azaadenine serves as a nucleobase mimic to investigate DNA/RNA replication mechanisms and enzyme kinetics. Researchers use it to develop antiviral or anticancer agents targeting nucleotide metabolism. It also aids in studying mutagenesis in genetic material. A: Always wear gloves, goggles, and lab coats to avoid skin/eye contact. Work in a ventilated area and follow OSHA/GHS guidelines for chemical handling. Refer to the Safety Data Sheet (SDS) for CAS 3976-69-0 before use. A: It is available through chemical suppliers like Sigma-Aldrich, Thermo Fisher, and specialized biotech vendors. Verify CAS 3976-69-0 and purity grades (≥95% HPLC) when ordering. Custom synthesis services may also provide it for research purposes. A: The key difference is the substitution of a nitrogen atom at position 8 in the purine ring, altering its hydrogen-bonding and reactivity. This modification impacts its interaction with enzymes like adenine deaminase. These structural changes make it valuable for probing biological systems.
Understanding 8-Azaadenine (3976-69-0) and Its Molecular Significance
Technical Superiority in Molecular Design
Competitive Supplier Analysis
Vendor
Purity
Price/Gram
Lead Time
Supplier A
99.1%
$142
4 weeks
Supplier B
98.7%
$165
6 weeks
Supplier C
99.4%
$155
3 weeks
Tailored Manufacturing Solutions
Clinical Research Implementation
Quality Assurance Standards
8-Azaadenine (3976-69-0) in Next-Gen Therapeutics
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