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4-Nitro Chloroformate High-Purity Reagent for Organic Synthesis
- Time of issue:May . 25, 2025 12:23
(Summary description)Tangshan Moneide Trading Co., Ltd. is a trading company specializing in the export of fine chemical products in China. Over the years, we have established good cooperative relations with many outstanding chemical production enterprises in China, and actively cooperated in research and development on some products. Our company's product series mainly include: electroplating chemicals, organic& inorganic fluoro chemicals, organic intermediate chemicals, phase transfer catalyst and Indicator or Biological stain .
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- Time of issue:2019-12-30 10:55
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(4 nitro chloroformate) 4 nitro chloroformate Our FlexiSynth™ technology enables: In peptide synthesis applications: Stability testing reveals: Recent developments include: (4 nitro chloroformate) A: 4 nitro chloroformate is primarily used as a reagent in organic synthesis, particularly for introducing carbamate groups. It is also employed in peptide coupling reactions and pharmaceutical intermediate production. A: They are the same compound. "4-nitrophenyl" and "p-nitrophenyl" both denote a nitro group in the para position on the benzene ring attached to the chloroformate group. A: Use protective gloves, goggles, and work in a well-ventilated area. Avoid contact with moisture, as it reacts to release toxic gases like hydrogen chloride and nitrous oxides. A: Its electrophilic nature enables efficient activation of carboxylic acids into reactive esters. These intermediates are critical for forming amide bonds in controlled reaction conditions. A: No, it should be stored refrigerated (2–8°C) in airtight containers under inert gas. Prolonged exposure to warmth or moisture degrades its reactivity and stability.
Understanding 4 Nitro Chloroformate Derivatives
and its structural analogs (4-nitrophenyl chloroformate, p-nitrophenyl chloroformate) represent high-reactivity intermediates with 83% annual growth in pharmaceutical applications since 2020. These compounds demonstrate:
Manufacturer Comparison: Technical Specifications
Parameter
Manufacturer A
Manufacturer B
Our Standard
Purity (%)
98.5
97.8
99.3
Moisture Content (ppm)
150
200
≤50
Batch Consistency
±2%
±3.5%
±0.8%
Customized Production Solutions
Industrial Application Performance Data
Optimal Storage Conditions
Storage Temp
6-Month Purity Retention
12-Month Purity Retention
-20°C
99.1%
98.7%
4°C
98.5%
97.2%
Advancing 4 Nitro Chloroformate Applications
FAQS on 4 nitro chloroformate
Q: What are the common applications of 4 nitro chloroformate?
Q: How does 4-nitrophenyl chloroformate differ from p-nitrophenyl chloroformate?
Q: What safety precautions are required when handling 4 nitro chloroformate?
Q: Why is 4-nitrophenyl chloroformate used in activated ester preparation?
Q: Can p-nitrophenyl chloroformate be stored at room temperature?