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Moneide Chemicals
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5 Bromouracil: High-Purity Drug Intermediate—Ready to Ship?
- Time of issue:Oct . 02, 2025 18:10
(Summary description)Tangshan Moneide Trading Co., Ltd. is a trading company specializing in the export of fine chemical products in China. Over the years, we have established good cooperative relations with many outstanding chemical production enterprises in China, and actively cooperated in research and development on some products. Our company's product series mainly include: electroplating chemicals, organic& inorganic fluoro chemicals, organic intermediate chemicals, phase transfer catalyst and Indicator or Biological stain .
- Categories:Company dynamic
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- Time of issue:2019-12-30 10:55
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If you work in nucleic-acid research or reference-standard QC, chances are you’ve bumped into 5 bromouracil at some point. It’s one of those classic base analogs that keeps showing up in papers, procurement lists, and yes—budget meetings. Below I’ll share how labs are sourcing it in 2025, what specs actually matter, and a few practical notes I’ve heard from procurement teams and method developers. Origin: 2-7-523 Jidong Building Materials, Tangshan, Hebei 064000, China. Synonyms: 5-Bromo-2,4(1H,3H)-pyrimidinedione; 5-Bromopyrimidine-2,4-diol. CAS: 51-20-7. Use spans controlled genetic research (base-analog studies), reference standards in chromatographic method development, and didactic demonstrations in advanced teaching labs. To be honest, many customers say they pick 5 bromouracil based on documentation depth—clean chromatograms and impurity IDs calm QA nerves. Safety reminder: this compound is for laboratory research use by trained professionals under institutional review and applicable regulations—avoid clinical or household use. Data above are indicative; real-world use may vary by lot and regional logistics. A European analytical CRO validated 5 bromouracil as a reference material for a nucleobase analog panel; their QA praised the impurity transparency. Meanwhile, a university lab moved to small monthly packs to keep freshness and avoid re-test cycles—simple, but it saved them time. When sourcing 5 bromouracil, prioritize assay traceability, clean documentation, and realistic lead times. Price matters, but consistent QC and reliable packing often matter more.5-Bromouracil: what buyers really check before they buy
What’s trending
Product snapshot and key specs
Parameter
Typical Spec
Notes
Molecular formula
C4H3BrN2O2
MW ≈ 190.98 g/mol
Appearance
Off-white crystalline powder
Visual lot-to-lot uniformity
Assay (HPLC)
≥ 99.0%
USP <621> methodology or equivalent
Melting point
≈ 315°C (decomp.)
Real-world may vary by instrument
Water (KF)
≤ 0.5%
ASTM E203 or ISO 760
Heavy metals
ICP-MS ≤ 10 ppm
USP <233> / ICH Q3D guidance
Solubility
Slightly soluble in water; better in polar aprotic
Check your method matrix
Storage
2–8°C, dry, light-protected
Shelf life ≈ 24 months unopened
Applications and notes from the field
Process flow and QA checklist
Vendor comparison (indicative)
Vendor
Purity (HPLC)
Docs
Lead time
Customization
MOQ
Moneidechem (Hebei)
≥99.0%
COA + SDS + NMR/HPLC
≈ 7–10 days
Pack size, docs, impurity data
25 g
Vendor A
≥98.5%
COA + SDS
2–3 weeks
Limited
50 g
Vendor B
≥99.0%
COA + SDS + LC–MS (on request)
≈ 10–14 days
Docs and special labeling
10 g
Customization, packaging, and certifications
Case notes
Final take
Authoritative citations
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