Moneide Chemicals
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1H-1,2,4-Triazole-3-Thiol Supplier Pharma & Agrochemical Grade
- Time of issue:May . 28, 2025 23:06
(Summary description)Tangshan Moneide Trading Co., Ltd. is a trading company specializing in the export of fine chemical products in China. Over the years, we have established good cooperative relations with many outstanding chemical production enterprises in China, and actively cooperated in research and development on some products. Our company's product series mainly include: electroplating chemicals, organic& inorganic fluoro chemicals, organic intermediate chemicals, phase transfer catalyst and Indicator or Biological stain .
- Categories:Company dynamic
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- Time of issue:2019-12-30 10:55
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(1h-1,2,4-triazole-3-thiol) 1H-1,2,4-Triazole-3-thiol derivatives demonstrate a 78% year-over-year growth in specialty chemical patents (2021-2023), reflecting their critical role in modern chemistry. These sulfur-containing heterocycles exhibit unique tautomeric properties, enabling dual functionality as hydrogen bond donors/acceptors. The global market for triazole-thiol compounds reached $420 million in 2023, driven by demand from pharmaceutical intermediates (42%), corrosion inhibitors (28%), and agrochemical precursors (19%). Comparative studies reveal 1H-1,2,4-triazole-3-thiol derivatives achieve 15-20% higher thermal stability (TGA analysis) versus conventional thiophenol analogs. Key performance parameters include: Advanced modification protocols enable: Pharma-grade 1-phenyl-1H-tetrazole-5-thiol batches demonstrate 99.4% API compatibility in accelerated stability testing (40°C/75% RH). Accelerated corrosion testing (ASTM G31) shows 3-mercapto-1,2,4-triazole formulations provide 1,200+ hours protection for copper substrates vs. 850 hours for benzotriazole standards. Electrochemical impedance spectroscopy confirms 10⁶ Ω·cm² polarization resistance in neutral media. A recent agrochemical formulation achieved 94% pest control efficiency using modified 1H-1,2,4-triazole-3-thiol ligands, reducing active ingredient requirements by 35%. Battery electrolyte additives derived from these compounds demonstrate 81% capacity retention after 500 cycles (0.5C rate). Ongoing research focuses on three strategic fronts: Projections indicate 22.4% CAGR through 2030, particularly in energy storage (38% sector growth) and targeted drug delivery systems (41% R&D increase). (1h-1,2,4-triazole-3-thiol) Q: What is the primary application of 1H-1,2,4-Triazole-3-thiol? A: It is widely used as a corrosion inhibitor in industrial processes. It also serves as a precursor in synthesizing heterocyclic compounds for pharmaceuticals and agrochemicals. Its thiol group enables metal-binding properties. Q: How is 3-Mercapto-1,2,4-triazole synthesized? A: It is typically synthesized by reacting thiourea with hydrazine hydrate under basic conditions. Cyclization and sulfur incorporation occur via heating. Catalysts like NaOH or KOH are often used to enhance yield. Q: What distinguishes 1-Phenyl-1H-tetrazole-5-thiol from 1H-1,2,4-Triazole-3-thiol? A: The former has a tetrazole ring (5-membered, 4N atoms) with a phenyl group, while the latter is a triazole (5-membered, 3N atoms). Their sulfur positions and ring structures differ, affecting reactivity. Q: Are these compounds hazardous to handle? A: Yes, they may cause skin/eye irritation due to thiol groups. Proper PPE (gloves, goggles) and ventilation are required. Always consult SDS for specific safety protocols. Q: Can 1H-1,2,4-Triazole-3-thiol act as a ligand in coordination chemistry? A: Yes, its sulfur and nitrogen atoms enable metal coordination. It forms stable complexes with transition metals like copper or zinc. Such complexes are studied for catalytic or antimicrobial applications.
Exploring the Versatility of 1H-1,2,4-Triazole-3-Thiol Derivatives
Technical Superiority in Molecular Engineering
Global Supplier Benchmarking Analysis
Supplier
Purity (%)
Price ($/kg)
Lead Time
Customization
Merck KGaA
99.8
1,450
6 weeks
Limited
Tokyo Chemical Industry
99.5
1,280
8 weeks
Moderate
Capot Chemical
99.2
980
4 weeks
Full
Tailored Molecular Design Services
Empirical Performance Validation
Industrial Implementation Success Metrics
Strategic Advancements in 1H-1,2,4-Triazole-3-Thiol Utilization
FAQS on 1h-1,2,4-triazole-3-thiol
What is the primary application of 1H-1,2,4-Triazole-3-thiol?
How is 3-Mercapto-1,2,4-triazole synthesized?
What distinguishes 1-Phenyl-1H-tetrazole-5-thiol from 1H-1,2,4-Triazole-3-thiol?
Are these compounds hazardous to handle?
Can 1H-1,2,4-Triazole-3-thiol act as a ligand in coordination chemistry?
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