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High Purity Fluorescein Disodium Salt CAS 518478 China Suppliers Factory
Fluorescein Disodium Salt is a high-performance, water-soluble sodium derivative of fluorescein, belonging to the synthetic xanthene dye family. Characterized by its vibrant orange-red crystalline form, this premium chemical compound transforms into a highly fluorescent yellow-green solution upon dissolution, offering superior solubility and stability compared to standard fluorescein acid.
Engineered for precision, it is widely utilized across medical diagnostics, ophthalmology, and industrial tracing. Its rigid molecular structure enables efficient light absorption and emission under blue light (490nm excitation), making it an indispensable tool for high-sensitivity fluorescence indication and redox monitoring in professional laboratory and clinical environments.
Detailed Parameters
| Chemical Name | Fluorescein Disodium Salt | CAS No. | 518-47-8 |
|---|---|---|---|
| Molecular Formula | C20H10Na2O5 | Molecular Weight | 376.27 |
| EINECS No. | 208-253-0 | Appearance | Orange-red crystal |
| Water Content | 7.0% max. | Water Solubility | Pass Test |
| Sensitivity Tests | Bromine/Acridine Yellow Qualified | Main Application | Fluorescence/REDOX Indicator |
Key Advantages
Enhanced Stability
The sodium salt form ensures improved chemical stability and consistency over a wide pH range.
Rapid Solubility
Dissolves readily in water to provide immediate, high-intensity fluorescence for urgent diagnostics.
High Quantum Yield
Intense yellow-green emission under 490nm blue light for exceptional visual clarity.
Clinical Precision
Ideal for retinal circulation examination and detecting corneal epithelial defects.
Versatile Utility
Applicable in ophthalmology, urology, neurosurgery, and industrial leak detection.
Low Toxicity
Regulatory approved with low systemic toxicity and rapid renal excretion.
Product Gallery
Management Platforms
Quality Control
Strict adherence to chemical purity standards for biological stain certification.
Synthesis Optimization
Advanced xanthene dye synthesis for consistent orange-red crystal morphology.
Regulatory Compliance
Meeting global safety protocols for medical and industrial diagnostic use.
Batch Traceability
Comprehensive tracking from raw organic intermediates to final salt production.
Inventory Management
Optimized storage conditions to maintain low moisture levels (max 7.0%).
Technical Support
Expert guidance on dilution and application for REDOX indicators.
Investment Return Comparison
| Performance Metric | Standard Fluorescein | Disodium Salt Grade |
|---|---|---|
| Water Solubility | Low/Difficult | Immediate/High |
| Stability (pH range) | Limited | Wide & Stable |
| Diagnostic Speed | Moderate | Rapid Response |
| Excitation Efficiency | Standard | Optimized (490nm) |
| Clinical Safety | Variable | High/Certified |
Frequently Asked Questions
Industrially, it is used as a highly efficient fluorescent tracer for water flow tracing in hydrological studies and leak detection in complex plumbing systems.
It is used for fluorescein angiography to examine retinal circulation and as a stain to identify corneal epithelial defects via eye drops.
Yes, it is globally approved for diagnostics. It has low systemic toxicity and is rapidly excreted by the kidneys, with adverse events occurring in less than 1% of cases.
The disodium salt form offers significantly improved water solubility and stability, making it far more suitable for intravenous and topical medical applications.
It requires blue light excitation, specifically around 490nm, to produce its characteristic high-intensity yellow-green fluorescence.
Contraindications include known hypersensitivity to the compound or severe renal impairment, which may require dosage adjustments.
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